LGC has published a review in the Journal of AOAC International on definitive approaches for the authentication of chondroitin, a supplement with a risk of serious adulteration.
Chondroitin is an over-the-counter food supplement often available in combination with glucosamine sulfate. It is sold widely for a number of uses for humans and animals and taken by many who suffer from osteoarthritis where it has been shown to have small to moderate benefits.
The paper, written in partnership with Queen’s University Belfast, makes key recommendations for forensically robust analysis of supplements containing chondroitin to prevent their adulteration with inferior substitutes.
Authors Michael Walker and Christopher Mussell (LGC), along with Professor Duncan Thorburn Burns (Institute of Global Food Security at Queen’s University Belfast), outlined the necessary steps to ensure the quality of chondroitin, including testing raw materials for currently known adulterants.
Michael Walker, Referee Analyst for the Government Chemist, said: “The Laboratory of the Government Chemist has had a long interest in the analysis of supplements containing chondroitin stemming from work carried out suggesting some were deficient of the declared amounts of chondroitin.”
Duncan Thorburn Burns, Professor at Institute of Global Food Security, Queen’s University Belfast, added: “As a natural polymer, routine analytical methods for chondroitin tend to be relatively nonspecific. Our paper demonstrates how to achieve the goal of affirming identity (including source) and purity.”